Constipation Home > Polyethylene Glycol 3350

Polyethylene glycol 3350 (PEG-3350) is a laxative used for treating occasional constipation. It works by drawing water into the colon, softening the stool, and increasing the frequency of bowel movements. The medicine comes in the form of a powder that is dissolved in a beverage and consumed once daily. Possible side effects may include nausea, diarrhea, and gas.

What Is Polyethylene Glycol 3350?

Polyethylene glycol 3350 (MiraLAX®) is an over-the-counter (OTC) medication used to treat occasional constipation. It belongs to a class of drugs called laxatives. Like all OTC medications, it is available without a prescription.
 
Polyethylene glycol 3350 (sometimes abbreviated as PEG-3350) was originally available by prescription only. In fact, a generic version is still available as a prescription medication. The prescription version is exactly the same as the over-the-counter version, but is more likely to be covered by insurance.
 
(Click What Is Polyethylene Glycol 3350 Used For? for more information on this topic, including possible off-label uses.)
 

Are There Side Effects?

Just like any medicine, polyethylene glycol 3350 can cause side effects. However, not everyone who uses the drug will experience problems. In fact, most people tolerate it quite well.
 
If reactions do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider. Serious side effects are less common.
 
Common side effects seen with polyethylene glycol 3350 may include but are not limited to:
 
  • Nausea
  • Abdominal (stomach) bloating
  • Abdominal (stomach) cramping
  • Gas
  • Diarrhea.
 
(Click Side Effects of Polyethylene Glycol 3350 to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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